ABSTRACT
Objective To investigate the safety, reliability and effectiveness of supra - aortic artery stenting angioplasty via transradial access in treating supra-aortic artery occlusion or stenosis. Methods The clinical data of 325 consecutive patients with supra-aortic artery occlusion or stenosis, who were admitted to authors' hospital during the period from January 2012 to January 2016 to receive stenting angioplasty, were retrospectively analyzed. According to patient's own will, the 325 patients were divided into transradial access group (n=52) and transfemoral access group (n=273). The results of the puncturing, the operative results, the duration of operation, the amount of intraoperative blood loss, the postoperative complications, the time of postoperative rest in bed, the average time of hospitalization of both groups were recorded. Results No statistically significant differences in the success rate of puncturing, the success rate of operation and the amount of intraoperative blood loss existed between the two groups (P＞0. 05). In 73. 1％ of patients (38/52) of the transradial access group the duration of operation was ≤30 min, while only in 43. 2％ of patients (118/ 273) of the transfemoral access group the duration of operation was ≤30 min, the difference between the two groups was statistically significant (P＜0. 000 1). After the operation, in transradial access group puncture point bleeding was seen in 8 patients and hematoma at the puncture site in one patient, the complication rate was 17. 3％ (9/52), while in transfemoral access group puncture point bleeding was observed in 23 patients, hematoma at the puncture site in 7 patients, pain of puncture site in one patient, and cerebral hemorrhage in one patient, the total complication rate was 11. 7％ (32/273); but the difference between the two groups was not statistically significant (χ2=1. 236, P=0. 266). Patients in the transradial access group could get out of bed immediately after the operation. No statistically significant difference in the average time of hospitalization existed between the two groups (P＞0. 05). Conclusion In performing endovascular stenting angioplasty for supra-aortic artery occlusion or stenosis, both transradial access and transfemoral access are safe, reliable and effective. Transradial access can be used as a replacement of transfemoral access. (J Intervent Radiol, 2018, 27:207-210)
ABSTRACT
Objective To observe the curative effect of Edaravone on intracerebral hemorrhage(ICH).Methods 122 ICH patients were randomly divided into Edaravone group(61 cases) and routine group(61 cases).On the basis of routine therapy for the two groups,the Edaravone group received Edaravone 30 mg with normal saline 100 ml intravenous drip twice a day for 14 d.The levels of serum S-100? protein(S-100?),neuron-specific enolase(NSE) were detected before and 3 d,7 d and 14 d after treatment.The score of neurologic dysfunction(NDS) was evaluated before and 7 d,14 d,28 d after treatment.The volumes of hematoma and edema were measured by skull CT scan before and 7 d,21 d after treatment.The curative effect and Barthel index(BI) were evaluated at 28 d and 90 d after treatment.Results Compared with before treatment,the levels of serum S-100? and NSE,the NDSs,the volumes of hematoma and edema were obviously improved at each time point after treatment in the two groups(all P